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Righolt, C.H. (author), Guffei, A. (author), Knecht, H. (author), Young, I.T. (author), Stallinga, S. (author), Van Vliet, L.J. (author), Mai, S. (author)Advances in light microscopy have enabled the visualization of DNA in the interphase nucleus with more detail than is visible with conventional light microscopy. The nuclear architecture is assumed to be different in cancer cells compared to normal cells. In this paper we have studied, for the first time, the organization of nuclear DNA and that...journal article 2014
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Zhao, Q. (author), Young, I.T. (author), De Jong, J.G.S. (author)We have constructed a mathematical model to analyze the photon efficiency of frequency-domain fluorescence lifetime imaging microscopy (FLIM). The power of the light source needed for illumination in a FLIM system and the signal-to-noise ratio of the detector have led us to a photon “budget.” These measures are relevant to many fluorescence...journal article 2011
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- Dietrich, H.R.C. (author), Rieger, B. (author), Wiertz, F.G.M. (author), De Groote, F.H. (author), Heering, H.A. (author), Young, I.T. (author), Garini, Y. (author) journal article 2009
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- Docter, M.W. (author), Van den Berg, P.M. (author), Alkemade, P.F.A. (author), Kutchoukov, V.G. (author), Piciu, O.M. (author), Bossche, A. (author), Young, I.T. (author), Garini, Y. (author) journal article 2007
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- Young, I.T. (author), Verbeek, P.W. (author), Mayall, B.H. (author) journal article 1986