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Langerak, A.J. (author), D'Olivo, P. (author), Thijm, O. S.A. (author), Regterschot, G.R.H. (author), Meskers, C. G.M. (author), Rozendaal, M.C. (author), Visch, V.T. (author), Bussmann, J.B.J. (author)Purpose: eHealth-based exercise therapies were developed to increase stroke patients’ adherence to home-based motor rehabilitation. However, these eHealth tools face a rapid decrease in use after a couple of weeks. This study investigates stroke patients’ motivation for home-based upper extremity rehabilitation with eHealth tools and their...journal article 2024
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Ross, Martin K. (author), Broz, F. (author), Baillie, Lynne (author)Repetitive, individual exercises can improve the functional ability of stroke survivors over the long term. With the aim of providing extra motivation to adhere to repetitive, individual rehabilitation, this paper presents a robotic coach for stroke rehabilitation. Our system uses the Pepper robot and performs one of twelve data-driven...conference paper 2024
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Albalak, Gali (author), Stijntjes, M. (author), van Bodegom, David (author), Jukema, J. Wouter (author), Atsma, Douwe E. (author), van Heemst, Diana (author), Noordam, Raymond (author)Aims Little is known about the impact of daily physical activity timing (here referred to as 'chronoactivity') on cardiovascular disease (CVD) risk. We aimed to examined the associations between chronoactivity and multiple CVD outcomes in the UK Biobank. Methods and results physical activity data were collected in the UK-Biobank through...journal article 2023
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Cahalane, R.M.E. (author), de Vries, J.J. (author), de Maat, Moniek P.M. (author), van Gaalen, Kim (author), van Beusekom, Heleen M. (author), van der Lugt, Aad (author), Fereidoonnezhad, B.F. (author), Akyildiz, A.C. (author), Gijsen, F.J.H. (author)Endovascular thrombectomy procedures are significantly influenced by the mechanical response of thrombi to the multi-axial loading imposed during retrieval. Compression tests are commonly used to determine compressive ex vivo thrombus and clot analogue stiffness. However, there is a shortage of data in tension. This study compares the tensile...journal article 2023
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Cahalane, R.M.E. (author), Akyildiz, A.C. (author), Kavousi, Maryam (author), Vernooij, Meike W. (author), Ikram, M. Kamran (author), Gijsen, F.J.H. (author), Bos, Daniel (author)Background The purpose of this study was to validate a technique for measuring mean calcium density and to determine associations of cardiovascular risk factors with carotid calcium density. Methods and Results We performed a cross-sectional study in a random sample of 100 stroke-free participants from the population-based Rotterdam Study....journal article 2023
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Rodriguez Hernandez, K.E. (author), de Groot, J.H. (author), Baas, Frank (author), Stijntjes, M. (author), Grootendorst, E.R.M. (author), Schiemanck, S.K. (author), van der Helm, F.C.T. (author), van der Kooij, H. (author), Mugge, W. (author)Individuals with an upper motor neuron syndrome, e.g., stroke survivors, may have a pathological increase of passive ankle stiffness due to spasticity, that impairs ankle function and activities such as walking. To improve mobility, walking aids such as ankle-foot orthoses and orthopaedic shoes are prescribed. However, these walking aids...journal article 2023
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Roelofs, Jolanda M.B. (author), Zandvliet, Sarah B. (author), Schut, I.M. (author), Huisinga, Anouk C.M. (author), Schouten, A.C. (author), Hendricks, Henk T. (author), de Kam, Digna (author), Aerden, Leo A.M. (author), Bussmann, J.B.J. (author), Geurts, Alexander C.H. (author), Weerdesteyn, Vivian (author)Background: After mild stroke persistent balance limitations may occur, creating a risk factor for fear of falling, falls, and reduced activity levels. Objective. To investigate whether individuals in the chronic phase after mild stroke show balance and gait limitations, elevated fall risk, reduced balance confidence, and physical activity...journal article 2023
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de Miguel-Fernández, Jesús (author), Lobo-Prat, Joan (author), Prinsen, Erik (author), Font-Llagunes, Josep M. (author), Marchal Crespo, L. (author)Background: In the past decade, there has been substantial progress in the development of robotic controllers that specify how lower-limb exoskeletons should interact with brain-injured patients. However, it is still an open question which exoskeleton control strategies can more effectively stimulate motor function recovery. In this review,...review 2023
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Ellis, Michael D. (author), Gurari, Netta (author), Gerritsen, Ninette T.A. (author), Lee, Sabrina M. (author), Wang, Amy (author), Dewald, J.P.A. (author)Muscle tissue is prone to changes in composition and architecture following stroke. Changes in muscle tissue of the extremities are thought to increase resistance to muscle elongation or joint torque under passive conditions. These effects likely compound neuromuscular impairments, exacerbating movement function. Unfortunately, conventional...journal article 2023
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Su, Ruisheng (author), van der Sluijs, P. Matthijs (author), Bobi, Joaquim (author), Taha, Aladdin (author), van Beusekom, Heleen M.M. (author), van der Lugt, Aad (author), Niessen, W.J. (author), Ruijters, Danny (author), van Walsum, T. (author)Background: X-ray digital subtraction angiography (DSA) is the imaging modality for peri-procedural guidance and treatment evaluation in (neuro-) vascular interventions. Perfusion image construction from DSA, as a means of quantitatively depicting cerebral hemodynamics, has been shown feasible. However, the quantitative property of perfusion...journal article 2023
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Venkatraghavan, Vikram (author), Voort, Sebastian R.van der (author), Bos, Daniel (author), Smits, M. (author), Barkhof, Frederik (author), Niessen, W.J. (author), Klein, Stefan (author), Bron, Esther E. (author)Computer-aided methods have shown added value for diagnosing and predicting brain disorders and can thus support decision making in clinical care and treatment planning. This chapter will provide insight into the type of methods, their working, their input data –such as cognitive tests, imaging, and genetic data– and the types of output they...book chapter 2023
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Lemke, M. (author), Rodríguez Ramírez, Edgar (author), Robinson, Brian (author)Stroke causes damage to the brain, often resulting in weakness or paralysis on one side of the body. Everyday objects such as smartphones can play an im-portant role after a stroke facilitating participation in daily activities. However, commercial smartphones can be challenging to use, and people with stroke of-ten adjust their behavior to...conference paper 2022
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Sui, Congbiao (author), de Vos, P. (author), Stapersma, D. (author), Visser, K. (author), Hopman, J.J. (author), Ding, Yu (author)Analysis of ship propulsion system performance is often performed using detailed hydrodynamic models to assess load changes, which are subsequently compared to static engine limits, or by detailed engine models that are rarely integrated with sufficiently detailed propulsion models for load change estimation. To investigate the dynamic engine...journal article 2022
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Su, Ruisheng (author), van der Sluijs, Matthijs (author), Cornelissen, Sandra A.P. (author), Lycklama, Geert (author), Hofmeijer, Jeannette (author), Majoie, Charles B.L.M. (author), Niessen, W.J. (author), van der Lugt, Aad (author), van Walsum, T. (author)Intracranial vessel perforation is a peri-procedural complication during endovascular therapy (EVT). Prompt recognition is important as its occurrence is strongly associated with unfavorable treatment outcomes. However, perforations can be hard to detect because they are rare, can be subtle, and the interventionalist is working under time...journal article 2022
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Luraghi, G. (author), Bridio, Sara (author), Lissoni, Vittorio (author), Dubini, Gabriele (author), Dwivedi, Anushree (author), McCarthy, Ray (author), Fereidoonnezhad, B.F. (author), McGarry, Patrick (author), Gijsen, F.J.H. (author)Mechanical thrombectomy (MT) treatment of acute ischemic stroke (AIS) patients typically involves use of stent retrievers or aspiration catheters alone or in combination. For in silico trials of AIS patients, it is crucial to incorporate the possibility of thrombus fragmentation during the intervention. This study focuses on two aspects of...journal article 2022
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van der Cruijsen, J. (author), Dooren, R.F. (author), Schouten, A.C. (author), Oostendorp, Thom F. (author), Frens, Maarten A. (author), Ribbers, G.M. (author), van der Helm, F.C.T. (author), Kwakkel, Gert (author), Selles, R.W. (author)Transcranial direct current stimulation (tDCS) is a promising tool to improve and speed up motor rehabilitation after stroke, but inconsistent clinical effects refrain tDCS from clinical implementation. Therefore, this study aimed to assess the need for individualized tDCS configurations in stroke, considering interindividual variability in...journal article 2022
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Su, Jiahang (author), Wolff, Lennard (author), van Doormaal, Pieter Jan (author), Dippel, Diederik W.J. (author), van Zwam, Wim (author), Niessen, W.J. (author), van der Lugt, Aad (author), van Walsum, T. (author)Purpose: The assessment of collateral status may depend on the timing of image acquisition. The purpose of this study is to investigate whether there are optimal time points in CT Perfusion (CTP) for collateral status assessment, and compare collaterals scores at these time points with collateral scores from multiphase CT angiography (mCTA)....journal article 2022
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Botonis, Olivia K. (author), Harari, Yaar (author), Embry, Kyle R. (author), Mummidisetty, Chaithanya K. (author), Riopelle, David (author), Giffhorn, Matt (author), Albert, Mark V. (author), Vallery, H. (author), Jayaraman, Arun (author)Background: Falls are a common complication experienced after a stroke and can cause serious detriments to physical health and social mobility, necessitating a dire need for intervention. Among recent advancements, wearable airbag technology has been designed to detect and mitigate fall impact. However, these devices have not been designed...journal article 2022
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Wenk, Nicolas (author), Buetler, Karin A. (author), Penalver-Andres, Joaquin (author), Müri, René M. (author), Marchal Crespo, L. (author)Background: The relearning of movements after brain injury can be optimized by providing intensive, meaningful, and motivating training using virtual reality (VR). However, most current solutions use two-dimensional (2D) screens, where patients interact via symbolic representations of their limbs (e.g., a cursor). These 2D screens lack depth...journal article 2022
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Padmos, R.M. (author), Arrarte Terreros, Nerea (author), Józsa, Tamás I. (author), Závodszky, Gábor (author), Marquering, Henk A. (author), Majoie, Charles B.L.M. (author), Payne, Stephen J. (author), Hoekstra, Alfons G. (author)The presence of collaterals and high thrombus permeability are associated with good functional outcomes after an acute ischaemic stroke. We aim to understand the combined effect of the collaterals and thrombus permeability on cerebral blood flow during an acute ischaemic stroke. A cerebral blood flow model including the leptomeningeal...journal article 2022