PTV-based VMAT vs. robust IMPT for head-and-neck cancer: A probabilistic uncertainty analysis of clinical plan evaluation with the Dutch model-based selection

Background and purpose: In the Netherlands, head-and-neck cancer (HNC) patients are referred for proton therapy (PT) through model-based selection (MBS). However, treatment errors may compromise adequate CTV dose. Our aims are: (i) to derive probabilistic plan evaluation metrics on the CTV consistent with clinical metrics; (ii) to evaluate...

Environmental sustainability and gynaecological surgery: Which factors influence behaviour? An interview study

Objective: To assess the various factors that influence environmentally sustainable behaviour in gynaecological surgery and examine the differences between gynaecologists and residents. Design: An interview study. Setting: Academic and non-academic hospitals in the Netherlands. Population: Gynaecologists (n = 10) and residents (n = 6)....

Crossroad decisions in deep endometriosis treatment options: a qualitative study among patients

Objective: To study the experiences, considerations, and motivations of patients with endometriosis in the decision-making process for deep endometriosis (DE) treatment options. Design: Qualitative study using semi-structured in-depth focus group methodology. Setting: University medical center. Patient(s): A total of 19 Dutch women diagnosed...

A comparative analysis of trajectory similarity measures

Computing trajectory similarity is a fundamental operation in movement analytics, required in search, clustering, and classification of trajectories, for example. Yet the range of different but interrelated trajectory similarity measures can be bewildering for researchers and practitioners alike. This paper describes a systematic comparison...

Fire-exposed continuous span composite steel-concrete slabs

From experimental evidence, it was concluded that existing rules for the calculation of the behaviour of fire-exposed composite beams and slabs often lead to conservative solutions. Furthermore, the range of common applications had grown beyond the limits of existing calculation rules. It was felt that existing rules lacked a fundamental basis,...

Partial fire protection of composite slabs