Orienting undirected phylogenetic networks

This paper studies the relationship between undirected (unrooted) and directed (rooted) phylogenetic networks. We describe a polynomial-time algorithm for deciding whether an undirected nonbinary phylogenetic network, given the locations of the root and reticulation vertices, can be oriented as a directed nonbinary phylogenetic network....

A near-linear kernel for bounded-state parsimony distance

The maximum parsimony distance d_MP(T₁,T₂) and the bounded-state maximum parsimony distance d_MP^t(T₁,T₂) measure the difference between two phylogenetic trees T₁,T₂ in terms of the maximum difference between their parsimony scores for any...

Making a Network Orchard by Adding Leaves

Phylogenetic networks are used to represent the evolutionary history of species. Recently, the new class of orchard networks was introduced, which were later shown to be interpretable as trees with additional horizontal arcs. This makes the network class ideal for capturing evolutionary histories that involve horizontal gene transfers. Here,...

Constructing phylogenetic networks via cherry picking and machine learning

Background: Combining a set of phylogenetic trees into a single phylogenetic network that explains all of them is a fundamental challenge in evolutionary studies. Existing methods are computationally expensive and can either handle only small numbers of phylogenetic trees or are limited to severely restricted classes of networks. Results: In...

Reconstructing Phylogenetic Networks via Cherry Picking and Machine Learning

Combining a set of phylogenetic trees into a single phylogenetic network that explains all of them is a fundamental challenge in evolutionary studies. In this paper, we apply the recently-introduced theoretical framework of cherry picking to design a class of heuristics that are guaranteed to produce a network containing each of the input...

A unifying characterization of tree-based networks and orchard networks using cherry covers

Phylogenetic networks are used to represent evolutionary relationships between species in biology. Such networks are often categorized into classes by their topological features, which stem from both biological and computational motivations. We study two network classes in this paper: tree-based networks and orchard networks. Tree-based...

Polynomial-Time Algorithms for Phylogenetic Inference Problems Involving Duplication and Reticulation

A common problem in phylogenetics is to try to infer a species phylogeny from gene trees. We consider different variants of this problem. The first variant, called Unrestricted Minimal Episodes Inference, aims at inferring a species tree based on a model with speciation and duplication where duplications are clustered in duplication episodes....

Not all phylogenetic networks are leaf-reconstructible

Unrooted phylogenetic networks are graphs used to represent reticulate evolutionary relationships. Accurately reconstructing such networks is of great relevance for evolutionary biology. It has recently been conjectured that all unrooted phylogenetic networks for at least five taxa can be uniquely reconstructed from their subnetworks obtained...

Deciding the existence of a cherry-picking sequence is hard on two trees

Here we show that deciding whether two rooted binary phylogenetic trees on the same set of taxa permit a cherry-picking sequence, a special type of elimination order on the taxa, is NP-complete. This improves on an earlier result which proved hardness for eight or more trees. Via a known equivalence between cherry-picking sequences and...