Collective dynamics and pattern formation in systems of communicating cells: Theory and Simulations

How a system of genetically identical biological cells organizes into spatially heterogeneous tissues is a central question in biology. Even when the molecular and genetic underpinnings of cell-cell interactions are known, how these lead to multicellular patterns is often poorly understood. Of particular interest are dynamic patterns such as...

Cellular Dialogues: Cell-Cell Communication through Diffusible Molecules Yields Dynamic Spatial Patterns

Cells form spatial patterns by coordinating their gene expressions. How a group of mesoscopic numbers (hundreds to thousands) of cells, without pre-existing morphogen gradients and spatial organization, self-organizes spatial patterns remains poorly understood. Of particular importance are dynamic spatial patterns such as spiral waves that...