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Höfler, G.T. (author), But, A. (author), Younes, S.H.H. (author), Wever, Ron (author), Paul, C.E. (author), Arends, I.W.C.E. (author), Hollmann, F. (author)The scale-up of chemoenzymatic bromolactonization to 100 g scale is presented, together with an identification of current limitations. The preparative-scale reaction also allowed for meaningful mass balances identifying current bottlenecks of the chemoenzymatic reaction.journal article 2020