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- Geraldes, Carlos F.G.C. (author), Castro, M. Margarida C.A. (author), Peters, J.A. (author) journal article 2022
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Geraldes, Carlos F.G.C. (author), Peters, J.A. (author)Molecular recognition involving glycoprotein-mediated interactions is ubiquitous in both normal and pathological natural processes. Therefore, visualization of these interactions and the extent of expression of the sugars is a challenge in medical diagnosis, monitoring of therapy, and drug design. Here, we review the literature on the...review 2022
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Geraldes, Carlos F.G.C. (author), Castro, M. Margarida C.A. (author), Peters, J.A. (author)Mn(III) porphyrins have great potential as Gd-free MRI contrast agents because both the cation and the ligand have interesting properties. The redox properties of the Mn(III)-ion can be exploited for the preparation of reactive oxygen species for therapy. Moreover, the porphyrin ligand allows these complexes to have a high affinity for tumor...review 2021
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Carvalho, Rui F.S. (author), Pereira, Giovannia A.L. (author), Rocha, João (author), Castro, M. Margarida C.A. (author), Granadeiro, Carlos M. (author), Nogueira, Helena I.S. (author), Peters, J.A. (author), Geraldes, Carlos F.G.C. (author)The NMR relaxivities of the decatungstolanthanoate core-shell nanoparticles, prepared by encapsulating [Ln(W<sub>5</sub>O<sub>18</sub>)<sub>2</sub>]<sup>9−</sup> polyoxometalates (LnPOM) within amorphous silica shells (K<sub>9</sub>[Ln(W<sub>5</sub>O<sub>18</sub>)<sub>2</sub>]@SiO<sub>2</sub>), were studied along the Ln series. The relaxivity...journal article 2021
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Peters, J.A. (author), Djanashvili, K. (author), Geraldes, Carlos F.G.C. (author), Platas-Iglesias, Carlos (author)In the periodical system, the lanthanides (the 15 elements in the periodic table between barium and hafnium) are unique in the sense that their trivalent cations have their valence electrons hidden behind the 5s and 5p electrons. They show a gradual decrease in ionic radius with increasing atomic number (also known as the lanthanide...review 2020
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Peters, J.A. (author), Geraldes, Carlos F.G.C. (author)A semi-empirical equation to estimate the hydration number of Mn(II) complexes was derived from a database of 49 previously published <sup>1</sup>H longitudinal Nuclear Magnetic Relaxation Dispersion profiles. This equation has the longitudinal <sup>1</sup>H relaxivity and the molecular weight of the Mn(II) complex under consideration as...journal article 2018
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Geraldes, C.F.G.C. (author), Djanashvili, K. (author), Peters, J.A. (author)Recently, many research activities in medical diagnosis have been devoted to molecular imaging with MRI. A key issue is the evaluation of molecular targets that allow the early detection and characterization of diseases and the assessment of the effects of therapy. The majority of the current targeting vectors are peptides and proteins; reports...journal article 2010
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Prata, M.I.M. (author), Ribeiro, M.J. (author), Santos, A.C. (author), Peters, J.A. (author), Nepveu, F. (author), Geraldes, C.F.G.C. (author), De Lima, J.J.P. (author)Aiming at radiopharmaceutical application, I111n3+ complexes of the polyaminocarboxylates TTHA, TTHA-bis(butylamide) and TTHA-bis(glucamide) were investigated. The in vitro stability of I111n(TTHA)3- and I111n(TTHA-bis(butylamide)- was evaluated by measuring the exchange of I111n3+ from the complexes to transferrin and the results were compared...journal article 1998