Print Email Facebook Twitter Ultrasound imaging of the brain using full-waveform inversion Title Ultrasound imaging of the brain using full-waveform inversion Author Taskin, U. (TU Delft ImPhys/Medical Imaging) Solberg Eikrem, Kjersti (NORCE Norwegian Research Centre AS) Naevdal, Geir (NORCE Norwegian Research Centre AS) Jakobsen, Morten (University of Bergen and Bjerknes Centre for Climate Research) Verschuur, D.J. (TU Delft ImPhys/Computational Imaging) van Dongen, K.W.A. (TU Delft ImPhys/Medical Imaging) Date 2020 Abstract Transcranial ultrasound has been used to image the brain since 1942. Currently, it is regaining interest and full-waveform inversion (FWI) methods are now employed to reconstruct speed-of-sound profiles of the brain. Many of these methods require a good starting model. Here, we test the applicability of contrast source inversion (CSI) as a FWI method to reconstruct two-dimensional speed-of-sound profiles of the soft brain tissue enclosed by the skull. The advantage of CSI is that it can handle large acoustic contrasts without the need for a good starting model. To test the performance of CSI, we first compute synthetic data. The resulting pressure field clearly shows a significant amount of multiple scattering caused by the skull that acts as a hard acoustic contrast. Next we invert the resulting synthetic data within the Born approximation as well as by applying CSI as a FWI method. The results clearly show that Born inversion can only image the soft brain tissue in the absence of the skull whereas it generates erroneous results when the skull is present. On the other hand, with CSI it is feasible to reconstruct both the skull and the soft brain tissue accurately. Importantly, as compared to other methods CSI does not require any a priori information about the contrast, a mask or a heterogeneous starting model to reconstruct the soft tissue enclosed by the skull. Subject BrainFull-waveform inversionQuantitative imagingSpeed-of-sound profileTranscranial ultrasound To reference this document use: http://resolver.tudelft.nl/uuid:57fe8977-527d-4816-b5ba-51f532656f62 DOI https://doi.org/10.1109/IUS46767.2020.9251665 Publisher IEEE, Piscataway, NJ, USA ISBN 9781728154480 Source IUS 2020 - International Ultrasonics Symposium, Proceedings Event 2020 IEEE International Ultrasonics Symposium, IUS 2020, 2020-09-07 → 2020-09-11, Las Vegas, United States Series IEEE International Ultrasonics Symposium, IUS, 1948-5719, 2020-September Part of collection Institutional Repository Document type conference paper Rights © 2020 U. Taskin, Kjersti Solberg Eikrem, Geir Naevdal, Morten Jakobsen, D.J. Verschuur, K.W.A. van Dongen Files PDF PID6622705_ius_2020_trans ... ttedv2.pdf 321.58 KB Close viewer /islandora/object/uuid:57fe8977-527d-4816-b5ba-51f532656f62/datastream/OBJ/view