Print Email Facebook Twitter Comparison of frequency-domain and continuous-wave near-infrared spectroscopy devices during the immediate transition Title Comparison of frequency-domain and continuous-wave near-infrared spectroscopy devices during the immediate transition Author Van Essen, Tanja (Erasmus MC) Goos, T.G. (TU Delft Medical Instruments & Bio-Inspired Technology; Erasmus MC) Van Ballegooijen, Liza (Erasmus MC) Pichler, Gerhard (Medical University Graz) Urlesberger, Berndt (Medical University Graz) Reiss, Irwin K.M. (Erasmus MC) De Jonge, Rogier C.J. (Erasmus MC) Date 2020 Abstract Background: Non-invasive monitoring of cerebral tissue oxygen saturation (rcSO2) during transition is of growing interest. Different near-infrared spectroscopy (NIRS) techniques have been developed to measure rcSO2. We compared rcSO2 values during the immediate transition in preterm neonates measured with frequency-domain NIRS (FD-NIRS) with those measured with continuous-wave NIRS (CW-NIRS) devices in prospective observational studies. Methods: We compared rcSO2 values measured with an FD-NIRS device during the first 15 min after birth in neonates with a gestational age ≥ 30 weeks but < 37 weeks born at the Erasmus MC- Sophia Children's Hospital, Rotterdam, the Netherlands, with similar values measured with a CW-NIRS device in neonates born at the Medical University of Graz, Austria. Mixed models were used to adjust for repeated rcSO2 measurements, with fixed effects for time (non-linear), device, respiratory support and the interaction of device and respiratory support with time. Additionally, parameters such as total haemoglobin concentration and oxygenated and deoxygenated haemoglobin concentrations measured by FD-NIRS were analysed. Results: Thirty-eight FD-NIRS measurements were compared with 58 CW-NIRS measurements. The FD-NIRS rcSO2 values were consistently higher than the CW-NIRS rcSO2 values in the first 12 min, irrespective of respiratory support. After adjustment for respiratory support, the time-dependent trend in rcSO2 differed significantly between techniques (p < 0.01). Conclusion: As cerebral saturation measured with the FD-NIRS device differed significantly from that measured with the CW-NIRS device, differences in absolute values need to be interpreted with care. Although FD-NIRS devices have technical advantages over CW-NIRS devices, FD-NIRS devices may overestimate true cerebral oxygenation and their benefits might not outweigh the usability of the more clinically viable CW-NIRS devices. Subject Continuous-waveFrequency-domainNear-infrared spectroscopyPreterm neonateTransition To reference this document use: http://resolver.tudelft.nl/uuid:a7798ddc-e48f-4211-9e64-f4191ebca6ce DOI https://doi.org/10.1186/s12887-020-1987-4 Source BMC Pediatrics, 20 (1) Part of collection Institutional Repository Document type journal article Rights © 2020 Tanja Van Essen, T.G. Goos, Liza Van Ballegooijen, Gerhard Pichler, Berndt Urlesberger, Irwin K.M. Reiss, Rogier C.J. De Jonge Files PDF s12887_020_1987_4.pdf 1008.72 KB Close viewer /islandora/object/uuid:a7798ddc-e48f-4211-9e64-f4191ebca6ce/datastream/OBJ/view