Pigmented paraaxillary located “complex” basal cell carcinoma imitating clinically irritated melanocytic lesion -succesfull surgical approach in Bulgarian patient

Journal article (2017)

Authors

Cristiana Voicu Polisano Clinic
Mara Madalina Mihai Carol Davila University of Medicine and Pharmacy
Serena Gianfaldoni University G. Marconi of Rome
Ilko Bakardzhiev Medical University of Varna
Hristo Mangarov Medical Institute of Ministry of Interior (MVR)
Georgi Tchernev Medical Institute of Ministry of Interior (MVR), Onkoderma” - Policlinic for Dermatology
Mihai Lupu Medas Medical Centre
James W. Patterson University of Virginia Health System
Nely Koleva Medical Institute of Ministry of Interior (MVR)
Uwe Wollina Academic Teaching Hospital Dresden-Friedrichstadt
T. Lotti Sapienza University of Rome, BT/Environmental Biotechnology - AS
Jacopo Lotti Sapienza University of Rome
Katlein França University of Miami Miller School of Medicine
Atanas Batashki Medical University of Plovdiv
Research Group
BT/Environmental Biotechnology (AS) (TU Delft)
Copyright: © 2017 Cristiana Voicu, Mara Madalina Mihai, Mihai Lupu, James W. Patterson, Nely Koleva, Uwe Wollina, T. Lotti, Jacopo Lotti, Katlein França, Atanas Batashki, Serena Gianfaldoni, Ilko Bakardzhiev, Hristo Mangarov, Georgi Tchernev
DOI: https://doi.org/10.3889/oamjms.2017.141
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Published Date

2017

Language

English

Faculty

Applied Sciences

Department

BT/Biotechnologie

Research Group

BT/Environmental Biotechnology

Abstract

Background: Basal cell carcinoma (BCC) is the most frequently encountered neoplasm worldwide. While nodular BCC is the most frequent clinical subtype, other forms of BCC, such as superficial, cystic, morpheiform, infiltrative, and pigmented may also be encountered. CASE PRESENTATION: We present the case of a 67-year-old male with a relatively well-defined infiltrative, pigmented plaque with multiple colours and peripheral growth situated in the right axillary region. The histopathologic examination performed after complete surgical excision of the tumour revealed a complex pigmented BCC with macronodular, fibroepithelioma-like, cystic, focally infiltrative and basosquamous features. Conclusion: Uncommon locations of BCCs in sun-protected areas such as the axillary region require a higher degree of suspicion for diagnosis. The complex histology of the presented case, including subtypes with differing biologic attributes, emphasises the importance of histopathological examination in the diagnosis and therapeutic management of BCC.