Scalable GPU Acceleration for Complex Brain Simulations

Complex mathematical models are used in computational neuroscience to stimulate brain activity to understand the biological processes involved. The simulation of such models is computationally costly, and thus highperformance<br/>computing systems are selected as a potential solution to increase performance.<br/>This thesis aims to implement a...

Analysing the performance of KHFAC nerve block stimulation parameters: Developing design considerations for blocking the pudendal nerve using a new gate-dependent block determination model

A major cause for voiding dysfunction is the inability to relax the urethral sphincter. KiloHertz Frequency Alternating Current (KHFAC) stimulation can block signals that are travelling through the body; applying this type of stimulation at the pudendal nerve could inhibit the pulses that lead to contraction of the urethral sphincter, and...

Encoding of Correlated Temporal Information in a Model Cerebellar Loop with Olivary Oscillators and Long-Term Plasticity

The olivocerebellar system plays a central role in motor learning, crucially contributing to the coordination, precision and accurate timing of movements. The system is formed by Purkinje cells (PC), the Deep Cerebellar Nucleus (DCN) and Inferior Olive (IO). Its input activate the PC which produces simple (SS) and complex spikes (CS). The latter...