Increasingly shortening product life cycles, regional market challenges and unforeseeable global events require highly iterative product and production adaptions. For faster adaptation, it is necessary to have a systematic understanding of the relationships between product design and production planning. A unified model and data structure are fundamental. Basic data must be extracted from both domains and integrated for consistent product-production co-design. For this purpose, we use a biological analogy, the genome-proteome phenomenon, to model the interdependencies of product (customer needs, functional requirements, design parameters) and production (technologies capabilities, machine information, process chain alternatives). From the genome, which represents the totality of available data of product and production, we contextualize the proteome, which represents an instance of a concrete product design and the corresponding production configuration. Thereby, one gene represents one incremental information set consisting of all above mentioned product and production information for a specific product function. For each of the mentioned information domains (e.g. product requirements) within a gene, a methodology exists (e.g. NLP) to model the interlinkage to the adjacent information domain (e.g. product function). Utilizing the interdependencies and heredity of product design and production planning enables quick analysis of adaptation-induced impact which will provide enhanced competitiveness in a volatile world.