Properties of adobe are highly dependent on the local soil composition and can vary significantly depending on fabrication techniques, configurations and state of conservation. The effect of the earthquakes that occurred in 2017 in Mexico relaunched discussion regarding the adequacy and safety of adobe-based constructions – a debate that involves many economic, cultural and social facets related to vernacular expressions and ways of life, long-term sustainability and risk management. In an effort to contribute to this, this paper includes and discusses a series of experiments carried out in typologically representative adobe constructions in the municipality of Tepoztlán (state of Morelos, Mexico). A campaign of ultrasonic pulse velocity tests was conducted on 13 historical buildings with the objective of assessing the variability of the adobe material present in those buildings. Some adobe units were then collected and tested in a laboratory to assess their compressive strength and stress/strain behaviour. From these two sets of experiments, it was possible to obtain valuable insights into the mechanical properties of the adobe that constitutes the characteristic housing typology in the region.