Study region: Island of Curaçao, Caribbean Sea Study focus: Groundwater is a critical resource for many Caribbean islands. This study assessed the groundwater quality (main and trace elements, E. coli) of Curaçao during 4 subsequent wet seasons (2020–2024). New hydrological insights for the region: Three main hydrochemical processes were identified with Principal Component Analysis (PCA): 1) seawater influence (median EC = 1900 µS/cm), 2) nutrient contamination, and 3) silicate weathering from altered basalts. Elevated median nitrate concentrations (all 206 samples = 35 mg/L) are highest in urban areas (102 mg/L) suggesting wastewater leakage from cesspits. Lower Cl/B mass ratios (550) in urban areas compared to natural vegetated (1000) areas, indicate a wastewater source derived from reverse osmosis drinking water relatively high in Boron. Enrichment of δ¹⁵N-NO₃ and δ¹⁸O-NO₃ versus wastewater signatures indicates considerable occurrence of denitrification. Phosphate concentrations remain low (∼0.1 mg/L), except for sites irrigated with large volumes of treated wastewater (>1 mg/L). Cl-B endmember mixing model showed 36 % wastewater contribution to groundwater, making it an important additional freshwater source given the semi-arid conditions. The findings underscore the value of comprehensive groundwater monitoring and the need for sanitation improvements. Addressing these challenges will benefit water management practices on Curaçao and similar islands. Additionally, it will improve groundwater quality, and groundwater-affected ecosystems, such as nearshore coral reefs.