S.J. Howe | TU Delft Repository

Insertional mutagenisis combined with acquiered somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

Journal article (2008) - S.J. Howe (author) , M.R. Mansour (author) , K.C. Gilmour (author) , S Adams (author) , SI Thornhill (author) , KL Parsley (author) , FJT Staal (author) , RE Gale (author) , DC Linch (author) , J Bayford (author) , L Brown (author) , M Quaye (author) , K. Schwarzwaelder (author) , C Kinnon (author) , P Ancliff (author) , DK Webb (author) , M. Schmidt (author) , C von Kalle (author) , H.B. Gaspar (author) , A.J. Trasher (author) , C. Bartholomae (author) , M. Hubank (author) , H. Kempski (author) , Martijn H. Brugman (author) , K Pike-Overzet (author) , S.J. Chatters (author) , D. De Ridder (author)

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-x1 gene therapy

Journal article (2007) - A Deichmann (author) , S Hacein-Bey-Abina (author) , A Fischer (author) , K. Schwarzwaelder (author) , ML Siegler (author) , Dick De Ridder (author) , K Pike-Overzet (author) , S.J. Howe (author) , AJ Thrasher (author) , G Wagemaker (author) , U Abel (author) , FJT Staal (author) , M. Schmidt (author) , E Delabesse (author) , JL Villeval (author) , B Aronow (author) , C Hue (author) , C Prinz (author) , M Wissler (author) , C Klanke (author) , J Weissenbach (author) , I Alexander (author) , N Fischer (author) , A Garrique (author) , C Kalle von (author) , M Cavazzana-Calvo (author) , Martijn H. Brugman (author) , J Hu (author) , H Glimm (author) , G Gyapay (author) , B Prum (author) , CC Fraser (author)

Gammaretrovirus-mediated correction of SCID-x1 is associated with skewed vector integration site distribution in vivo

Journal article (2007) - K. Schwarzwaelder (author) , S.J. Howe (author) , K.L. Parsley (author) , K.C. Gilmour (author) , JL Sinclair (author) , J Bayford (author) , R Peraj (author) , K Pike-Overzet (author) , FJT Staal (author) , S Schmidt (author) , D. de Ridder (author) , C Kinnon (author) , Martijn H. Brugman (author) , U Abel (author) , G Wagemaker (author) , H.B. Gaspar (author) , AJ Thrasher (author) , C Kalle von (author) , A Deichmann (author) , H Glimm (author) , M Schmidt (author) , C Prinz (author) , M Wissler (author) , D.J.S. King (author) , F Zhang (author)

Ectopic retroviral expression of LMO2, but not IL2Ry, blocks human T-cell development from CD34+ cells: implications for leukemogenesis in gene therapy

Journal article (2007) - K Pike-Overzet (author) , D. de Ridder (author) , JJM van Dongen (author) , FJT Staal (author) , F Weerkamp (author) , MRM Baert (author) , MMA Verstegen (author) , Martijn H. Brugman (author) , S.J. Howe (author) , M. J.T. Reinders (author) , AJ Thrasher (author) , G Wagemaker (author)