This study examines the local, intratidal effects of suspended sediment concentrations (SSCs) on the hydrodynamics and vertical mixing in the Ems Estuary, located on the border between Germany and The Netherlands, during summer and winter seasons when the estuary turbidity maximum (ETM) is located upstream and adjacent to the study site, respectively. Measurements of density, SSCs, turbulent kinetic energy dissipation, and current velocity were collected and analyzed over a semi-diurnal tidal cycle in August of 2018 and January of 2019 as part of the collaborative Ems-Dollard Measurement (EDoM) campaign. During August, the estuary turbidity maximum was located 25 km upstream from the measurement site and local SSCs were low. Results revealed that under these conditions, suspended sediment minimally impacted vertical mixing by stabilizing density near-bottom during flood tide, while typical salinity-induced tidal straining patterns dominated. During January, the ETM was located only 5 km upstream of the measurement site leading to higher local sediment concentrations. Salinity-induced straining of the density occurred on early flood tide, creating stratification that suppressed vertical mixing. The suppression was enhanced by the contribution of vertical gradients in SSC to density, as signified by the gradient Richardson number. Suppression of vertical mixing by sediment-enhanced stratification was most significant within the hour following maximum flood currents when elevated velocity shear occurred. The variability observed between the local dynamics during August and January were attributed to greater sediment concentrations due to the ETM proximity in January. The intratidal asymmetry of vertical mixing observed under higher SSCs likely has implications for sediment transport.