A cell-based smoothed discrete shear gap method (CS-DSG3) based on the first-order shear deformation theory was recently proposed for static and dynamics analyses of Mindlin plates. In this paper, the CS-DSG3 is extended for analysis and active vibration control of the functionally graded material (FGM) plates integrated with piezoelectric sensors and actuators. In the piezoelectric FGM plates, the properties of core material are assumed to be graded through the thickness by the power law distribution while the electric potential is assumed to be a linear function through the thickness of each piezoelectric sub-layer. A closed-loop control algorithm based on the displacement and velocity feedbacks is used to control static deflection and active vibration of piezoelectric FGM plates. Several numerical examples are conducted to demonstrate the reliability and accuracy of the proposed method compared to other available numerical results.