The multimedia and multimodal community is witnessing an explosive transformation in the recent years with major societal impact. With the unprecedented deployment of multimedia devices and systems, multimedia research is critical to our abilities and prospects in advancing state-of-the-art technologies and solving real-world challenges facing the society and the nation. To respond to these challenges and further advance the frontiers of the field of multimedia, this panel will discuss the challenges and visions that may guide future research in the next ten years.