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Rational design of enantioselective biotransformations in organic media. Towards a comprehensive model for solvent-induced changes of lipase enantioselectivity.

Book chapter - JA Jongejan, PLA Overbeeke

Activity and enantioselectivity of modified lipases in organic solvents.

Journal article - PLA Overbeeke, BC Koops, HM Verheij, AJ Slotboom, MR Egmond, JA Jongejan, J.J. Heijnen

Lipase-catalyzed kinetic resolutions in organic solvents. Influence of process variables on enzyme enantioselectivity.

Journal article - PLA Overbeeke

Solvent effect on lipase enantioselectivity. Evidence for the presence of two thermodynamic states.

Journal article - PLA Overbeeke, JA Jongejan, J.J. Heijnen

Biocatalytic synthesis of cyclopropanol from cyclopropyl methyl ketone using whole cells of Rhodococcus erythropolis

Journal article - PLA Overbeeke, P Schenkels, F Secundo, JA Jongejan

Enantioselectivity of Candida rugosa lipase in the hydrolysis of 2-chloroproionic acid methyl ester

Journal article - PLA Overbeeke, JA Jongejan

Influence of lid conformation on lipase enantioselectivity.

Journal article - PLA Overbeeke, C Govardhan, N Khalaf, JA Jongejan, J.J. Heijnen

Kluyver Institute for Biotechnology in The Netherlands - Unity in Biochemistry.

Journal article - JL den Hollander, JJ Beun, PLA Overbeeke, J Schalk

Biotechnology in The Netherlands.

Journal article - JJ Beun, JL den Hollander, PLA Overbeeke, J Schalk

Optimization of Pseudomonas cepacia lipase preparations for catalysis in organic solvents

Journal article - F Secundo, S Spadaro, G Carrea, PLA Overbeeke

Simple conformation space search protocols for the evaluation of enantioselectivity of lipases.

Journal article - SC Orrenius, C van Heusden, J van Ruiten, PLA Overbeeke, H Kierkels, JA Duine, JA Jongejan

The Saccharomyces cerevisiae TGL2 gene encodes a protein with lipolytic activity and can complement an Escherichia coli diacylglycerol kinase disruptant.

Journal article - GPH van Heusden, M Nebohacova, PLA Overbeeke, HY Steensma

Enthalpic and entropic contributions to lipase enantioselectivity.

Journal article - PLA Overbeeke, SC Orrenius, JA Jongejan, JA Duine

Organic cosolvents restore the inherently high enantiomeric ratio of lipase-B from candida-antarctica in hydrolytic resolution by relieving the enantiospecific inhibition of product alcohol.

Journal article - K Lundhaug, PLA Overbeeke, JA Jongejan, T Anthonsen

The temperature dependence of enzyme kinetic resolutions reveals the relative importance of enthalpy and entropy to enzyme enantioselectivity

Journal article - PLA Overbeeke, J Ottosson, K Hult, JA Jongejan, JA Duine

Influence of process variables on the enantioselectivity of lipase-catalyzed kinetic resolutions in organic solvents

Doctoral thesis - PLA Overbeeke

PLA Overbeeke

Authored