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document
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Elbatsh, Ahmed M.O. (author), Kim, E. (author), Eeftens, J.M. (author), Raaijmakers, Jonne A. (author), van der Weide, Robin H. (author), GarcĂa-Nieto, Alberto (author), Bravo, Sol (author), Ganji, M. (author), Dekker, C. (author)
Condensin is a conserved SMC complex that uses its ATPase machinery to structure genomes, but how it does so is largely unknown. We show that condensin's ATPase has a dual role in chromosome condensation. Mutation of one ATPase site impairs condensation, while mutating the second site results in hyperactive condensin that compacts DNA faster...
journal article 2019
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