Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer

Journal article (2018)

Authors

Tesa M. Severson Netherlands Cancer Institute
Yongsoo Kim Netherlands Cancer Institute
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Stacey E.P. Joosten Netherlands Cancer Institute
Karianne Schuurman Netherlands Cancer Institute
Petra Van Der Groep University Medical Center Utrecht
Cathy B. Moelans University Medical Center Utrecht
Natalie D. ter Hoeve University Medical Center Utrecht
Quirine F. Manson University Medical Center Utrecht
J.W.M. Martens Erasmus MC, Cancer Genomics Centre, Dutch Breast Cancer Research Group
L.F.A. Wessels Cancer Genomics Centre, Netherlands Cancer Institute, Pattern Recognition and Bioinformatics - EEMCS
Research Group
Pattern Recognition and Bioinformatics (EEMCS) (TU Delft)
Copyright: © 2018 Tesa M. Severson, Yongsoo Kim, Stacey E.P. Joosten, Karianne Schuurman, Petra Van Der Groep, Cathy B. Moelans, Natalie D. Ter Hoeve, Quirine F. Manson, J.W.M. Martens, L.F.A. Wessels, More Authors
DOI
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https://doi.org/10.1038/s41467-018-02856-2
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Published Date

2018

Language

English

Reuse Rights

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Faculty

Electrical Engineering, Mathematics and Computer Science

Department

Intelligent Systems

Research Group

Pattern Recognition and Bioinformatics

Abstract

Male breast cancer (MBC) is rare and largely hormonally driven. Here, the authors examine the action of steroid hormone receptors in male and female breast cancers and find gender selective hormone receptor action that associates with the survival of MBC patients.