Numerical simulations of flow patterns in the human left ventricle model with a novel dynamic mesh morphing approach based on radial basis function

Journal Article (2021)
Author(s)

Fei Xu (External organisation)

S. Kenjeres (TU Delft - ChemE/Transport Phenomena)

Research Group
ChemE/Transport Phenomena
Copyright
© 2021 Fei Xu, S. Kenjeres
DOI related publication
https://doi.org/10.1016/j.compbiomed.2020.104184
More Info
expand_more
Publication Year
2021
Language
English
Copyright
© 2021 Fei Xu, S. Kenjeres
Research Group
ChemE/Transport Phenomena
Volume number
130
Reuse Rights

Other than for strictly personal use, it is not permitted to download, forward or distribute the text or part of it, without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license such as Creative Commons.

Abstract

We present a new numerical simulation framework for prediction of flow patterns in the human left ventricle model. In this study, a radial basis function (RBF) mesh morphing method is developed and applied within the finite-volume computational fluid dynamics (CFD) approach. The numerical simulations are designed to closely mimic details of recent tomographic particle image velocimetry (TomoPIV) experiments. The numerically simulated dynamic motions of the left ventricle and tri-leaflet biological mitral valve are emulated through the RBF morphing method. The arbitrary Lagrangian-Eulerian (ALE) based CFD is performed with the RBF-defined deforming wall boundaries. The results obtained show a good agreement with experiments, confirming the reliability and accuracy of the developed simulation framework.