A Biocatalytic Aza-Achmatowicz Reaction

Journal article (2016)

Authors

E. Fernandez Fueyo BT/Biocatalysis - AS
S.H.H. Younes Sohag University, BT/Biocatalysis - AS
Stefan Van Rootselaar Radboud Universiteit Nijmegen
René W M Aben Radboud Universiteit Nijmegen
R. Renirie IVAM UvA BV
Ron Wever Universiteit van Amsterdam
Dirk Holtmann DECHEMA Research Institute
Floris P.J.T. Rutjes Radboud Universiteit Nijmegen
F. Hollmann BT/Biocatalysis - AS
Research Group
BT/Biocatalysis (AS) (TU Delft)
Copyright: © 2016 E. Fernandez Fueyo, S.H.H. Younes, Stefan Van Rootselaar, René W M Aben, R. Renirie, Ron Wever, Dirk Holtmann, Floris P J T Rutjes, F. Hollmann
DOI
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https://doi.org/10.1021/acscatal.6b01636
Biocatalysis Oxidation Peroxidase Achmatowicz reaction Hypohalogenites
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Published Date

2016

Language

English

Reuse Rights

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Faculty

Applied Sciences

Department

BT/Biotechnologie

Research Group

BT/Biocatalysis

Abstract

A catalytic, enzyme-initiated (aza-) Achmatowicz reaction is presented. The involvement of a robust vanadium-dependent peroxidase from Curvularia inaequalis allows the simple use of H2O2 and catalytic amounts of bromide.