Chiral amine synthesis by oxidoreductases
E.P.J. Jongkind (TU Delft - BT/Biocatalysis)
C. E. Paul – Promotor (TU Delft - BT/Biocatalysis)
U Hanefeld – Promotor (TU Delft - BT/Biocatalysis)
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Abstract
Chiral amines are valuable compounds in the pharmaceutical industry. These valuable compounds have been made via organocatalysis, metallocatalysis but in the last two decades also via biocatalysis. Enzymes are highly selective, making them attractive catalysts to target chiral amine synthesis. The aim of this dissertation was to apply different biocatalytic pathways with oxidoreductases to synthesize chiral amines.
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