Progress toward Quantitative Design Principles of Multicellular Systems

Book Chapter (2017)
Author(s)

E. Pavinato Olimpio (Kavli institute of nanoscience Delft, TU Delft - OLD BN/Hyun Youk Lab)

D.R. Gomez Alvarez (TU Delft - OLD BN/Hyun Youk Lab, Kavli institute of nanoscience Delft)

H.O. Youk (TU Delft - OLD BN/Hyun Youk Lab, Kavli institute of nanoscience Delft)

Research Group
OLD BN/Hyun Youk Lab
Copyright
© 2017 E. Pavinato Olimpio, D.R. Gomez Alvarez, H.O. Youk
DOI related publication
https://doi.org/10.1002/9783527696130.ch13
More Info
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Publication Year
2017
Language
English
Copyright
© 2017 E. Pavinato Olimpio, D.R. Gomez Alvarez, H.O. Youk
Research Group
OLD BN/Hyun Youk Lab
Bibliographical Note
Accepted Author Manuscript@en
ISBN (print)
9783527335589
ISBN (electronic)
9783527696130
Reuse Rights

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Abstract

Living systems, particularly multicellular systems, often seem hopelessly complex. But recent studies have suggested that, beneath this complexity, there may be unifying quantitative principles that are only now starting to unravel. All cells interact with their environments and with other cells. Communication among cells is a primary means for cells to interact with each other. The complexity of these multicellular systems, due to the large numbers of cells and the diversity of intracellular and intercellular interactions, makes understanding multicellular systems a daunting task. To overcome this challenge, we will likely need judicious simplifications and conceptual frameworks, which can reveal design principles that are shared among diverse multicellular systems. Here we review some recent progress toward developing such frameworks.

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