MIMO-decoupling to improve pressure and flow tracking in mechanical ventilation
Lars Van De Kamp (Demcon Life Sciences and Health, Eindhoven University of Technology)
Isabelle Franklin (Demcon Life Sciences and Health)
Bas Van Loon (Demcon Life Sciences and Health)
Tom Oomen (Eindhoven University of Technology, TU Delft - Team Jan-Willem van Wingerden)
Nathan Van De Wouw (Eindhoven University of Technology)
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Abstract
Mechanical ventilators are complex mechatronic devices that are essential for patients who are unable to breathe independently. The aim of this paper is to develop a systematic control method that achieves accurate tracking of both the pressure and flow to ensure comfortable breathing for the patient. This is achieved by using a feedback design procedure technique based on static decoupling and the factorized Nyquist criterion. Furthermore, switching controllers are introduced that allow for improved baseflow tracking performance. The presented control method is implemented in a real ventilator and it is demonstrated that the tracking performance is improved by conducting an experimental case-study.
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File under embargo until 21-02-2026