Reduced quality of life in living kidney donors

Association with fatigue, societal participation and pre-donation variables

Journal article (2012)

Authors

Ingrid B. De Groot Leiden University Medical Center
A.M. Stiggelbout Leiden University Medical Center
Paul J.M. van der Boog Leiden University Medical Center
Andrzej G. Baranski Leiden University Medical Center
P.J. Marang-van de Mheen Leiden University Medical Center
Affiliation
External organisation
Expectations Kidney donors Reduced health related quality of life Relationship changes Societal participation
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Published Date

2012

Language

English

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Affiliation

External organisation

Abstract

Health related quality of life (HRQoL) of living kidney donors on average is good, but some donors experience a low HRQoL after donation. This study assessed the prevalence of reduced HRQoL and explored associations with pre- and post-donation variables. 316 donors (response rate 74%) who donated a kidney between 1997 and 2009 filled in a questionnaire. HRQoL was measured using the Short-Form 36; fatigue using the Multidimensional Fatigue Inventory; societal participation using the Utrecht Scale for Evaluation of Rehabilitation- Participation. Donors on average had better HRQoL than the general population. However, 12% had a reduced physical (PCS) and 18% a reduced mental (MCS) HRQoL. Donors with reduced HRQoL reported greater fatigue (P < 0.01), lower societal participation (P < 0.01) and showed a trend towards statistical significance in experiencing more donor-recipient relationship changes (P = 0.07). Prior to donation, donors with reduced PCS had a higher BMI (P < 0.05) and more often smoked (P < 0.05). Donors with reduced MCS had higher expectations (P < 0.05). Reduced HRQoL is associated with higher BMI, smoking and higher expectations prior to donation. These results may be used to develop a screening instrument to select donors at high risk for reduced HRQoL.