Scale-spaces from protein networks

How diffusion profiles reveal functional information in physical interaction topologies

Poster (2012)
Author(s)

Christos Dimitrakopoulos (University of Patras)

Marc Hulsman (TU Delft - Pattern Recognition and Bioinformatics)

Jeroen de Ridder (TU Delft - Pattern Recognition and Bioinformatics)

Research Group
Pattern Recognition and Bioinformatics
More Info
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Publication Year
2012
Language
English
Research Group
Pattern Recognition and Bioinformatics
Pages (from-to)
1-1

Abstract

Summary

Understanding the living cell as a system of interconnected components is one of the key contemporary challenges. This is a complex problem, in which different types of functional interactions play a role, each operating across multiple distinct scales.

How do functional interactions emerge
from the topology of the physical interaction network?

To investigate this we explore scale independent descriptions of the topology of the physical protein-protein and protein-DNA interaction networks in yeast.

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