Intraoperative tumor margin assessment using diffuse reflectance spectroscopy
The effect of electrosurgery on tissue discrimination using ex vivo animal tissue models
Sara Azizian Amiri (TU Delft - Medical Instruments & Bio-Inspired Technology)
Carlijn M. van Gent (Student TU Delft)
Jenny Dankelman (TU Delft - Medical Instruments & Bio-Inspired Technology)
Benno H.W. Hendriks (Philips Research, TU Delft - Medical Instruments & Bio-Inspired Technology)
More Info
expand_more
Other than for strictly personal use, it is not permitted to download, forward or distribute the text or part of it, without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license such as Creative Commons.
Abstract
Using an intraoperative margin assessment technique during breast-conserving surgery (BCS) helps surgeons to decrease the risk of positive margin occurrence. Diffuse reflectance spectroscopy (DRS) has the potential to discriminate healthy breast tissue from cancerous tissue. We investigated the performance of an electrosurgical knife integrated with a DRS on porcine muscle and adipose tissue. Characterization of the formed debris on the optical fibers after electrosurgery revealed that the contamination is mostly burned tissue. Even with contaminated optical fibers, both tissues could still be discriminated with DRS based on fat/water ratio. Therefore, an electrosurgical knife integrated with DRS may be a promising technology to provide the surgeon with real-time guidance during BCS.
help_outline