The curious case of curvature
Geometric perspectives on biomaterial design
S.J.P. Callens (TU Delft - Biomaterials & Tissue Biomechanics)
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Abstract
The rapidly expanding field of tissue engineering presents enticing, yet demanding challenges for scientists and engineers across many different disciplines. The ultimate goal of tissue engineering is ambitious: to regenerate damaged or missing tissue in its full complexity, either in vitro or in situ, and restore organ function. In addition to cells and biochemical factors, biomaterial scaffolds form the other essential ingredient within the tissue engineering paradigm. These scaffolds support, guide, and stimulate neotissue formation and are rationally designed to meet the desired balance between mechanical, mass transport and biological properties necessary for regeneration and implantation.
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