The curious case of curvature

Geometric perspectives on biomaterial design

Doctoral thesis (2021)

Authors

S.J.P. Callens Biomaterials & Tissue Biomechanics - Mechanical, Maritime and Materials Engineering
Research Group
Biomaterials & Tissue Biomechanics (Mechanical, Maritime and Materials Engineering) (TU Delft)
Copyright: © 2021 S.J.P. Callens
DOI: https://doi.org/10.4233/uuid:6d8f6160-5e1c-4396-a6c2-0bc67c3858b9
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Published Date

2021

Language

English

Faculty

Mechanical, Maritime and Materials Engineering

Department

Biomechanical Engineering

Research Group

Biomaterials & Tissue Biomechanics

Abstract

The rapidly expanding field of tissue engineering presents enticing, yet demanding challenges for scientists and engineers across many different disciplines. The ultimate goal of tissue engineering is ambitious: to regenerate damaged or missing tissue in its full complexity, either in vitro or in situ, and restore organ function. In addition to cells and biochemical factors, biomaterial scaffolds form the other essential ingredient within the tissue engineering paradigm. These scaffolds support, guide, and stimulate neotissue formation and are rationally designed to meet the desired balance between mechanical, mass transport and biological properties necessary for regeneration and implantation.