Building a community to engineer synthetic cells and organelles from the bottom-up
Oskar Staufer (Max Planck Institute for Medical Research, University of Bristol)
Jacqueline A. DE LORA (Max Planck Institute for Medical Research)
Eleonora Bailoni (Rijksuniversiteit Groningen)
Alisina Bazrafshan (Emory University)
Amelie S. Benk (Max Planck Institute for Medical Research)
Kevin Jahnke (Max Planck Institute for Medical Research)
Zachary A. Manzer (Cornell University)
Marileen Dogterom (TU Delft - Applied Sciences, BaSyc Consortium)
Gabriel P. López (University of New Mexico)
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Abstract
Employing concepts from physics, chemistry and bioengineering, 'learning-by-building' approaches are becoming increasingly popular in the life sciences, especially with researchers who are attempting to engineer cellular life from scratch. The SynCell2020/21 conference brought together researchers from different disciplines to highlight progress in this field, including areas where synthetic cells are having socioeconomic and technological impact. Conference participants also identified the challenges involved in designing, manipulating and creating synthetic cells with hierarchical organization and function. A key conclusion is the need to build an international and interdisciplinary research community through enhanced communication, resource-sharing, and educational initiatives.