Production of Co-58m in a siphon-style liquid target on a medical cyclotron

Journal article (2023)

Authors

L. Mues genannt Koers TRIUMF, University of British Columbia
S. W. McNeil TRIUMF
Valery Radchenko TRIUMF, University of British Columbia
E. Paulssen FH Aachen University of Applied Sciences, RST/Applied Radiation & Isotopes - AS
Cornelia Hoehr TRIUMF, University of Victoria, University of British Columbia
Research Group
RST/Applied Radiation & Isotopes (AS) (TU Delft)
Copyright: © 2023 L. Mues genannt Koers, S. W. McNeil, V. Radchenko, E. Paulssen, C. Hoehr
DOI
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https://doi.org/10.1016/j.apradiso.2023.110734
Cobalt-58m Cyclotron production Liquid target Meitner-Auger therapy Radiometal Small medical cyclotron
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Published Date

2023

Language

English

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Faculty

Applied Sciences

Department

RST/Radiation, Science and Technology

Research Group

RST/Applied Radiation & Isotopes

Abstract

We present the production of 58mCo on a small, 13 MeV medical cyclotron utilizing a siphon style liquid target system. Different concentrated iron(III)-nitrate solutions of natural isotopic distribution were irradiated at varying initial pressures and subsequently separated by solid phase extraction chromatography. The radio cobalt (58m/gCo and 56Co) was successfully produced with saturation activities of (0.35 ± 0.03) MBq μA−1 for 58mCo with a separation recovery of (75 ± 2) % of cobalt after one separation step utilizing LN-resin.