High-Density and Resolution Epicardial Mapping of the Atria
Translational Research with Clinical Impact
Ziliang Ye (Erasmus MC)
Yifan Jia (Erasmus MC)
Mathijs S. van Schie (Erasmus MC)
Paul Knops (Erasmus MC)
Vehpi Yildirim (Erasmus MC)
Yannick J.H.J. Taverne (Erasmus MC)
Natasja M.S. de Groot (TU Delft - Signal Processing Systems, Erasmus MC)
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Abstract
The electrical arrhythmogenic substrate underlying the most common cardiac arrhythmia atrial fibrillation (AF) may consist of conduction disorders, low-voltage areas, or fractionated potentials. High-density and resolution epicardial mapping (HDREM) approaches have been introduced to quantify and visualize electrophysiological properties of the atria. These approaches are essential for obtaining innovative insights into arrhythmogenic substrates and identifying novel targets for therapy. The aim of this review is to summarize and discuss the (1) contribution of HDREM studies to the knowledge on atrial arrhythmogenesis and (2) future applications of HDREM of atria in daily clinical practice.
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