Influence of the accuracy of angiography-based reconstructions on velocity and wall shear stress computations in coronary bifurcations

A phantom study

Journal article (2015)
Department
ImPhys/Imaging Physics (AS) (TU Delft)
Copyright: This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Published Date

31-12-2015

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Source:

PLoS One, 10(12) 2015

ISSN:

1932-6203

Faculty

Applied Sciences

Department

ImPhys/Imaging Physics

Abstract

Wall shear stress (WSS) plays a key role in the onset and progression of atherosclerosis in human coronary arteries. Especially sites with low and oscillating WSS near bifurcations have a higher propensity to develop atherosclerosis. WSS computations in coronary bifurcations can be performed in angiography-based 3D reconstructions. It is essential to evaluate how reconstruction errors influence WSS computations in mildly-diseased coronary bifurcations. In mildly-diseased lesions WSS could potentially provide more insight in plaque progression.

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