Independent Component Analysis for Noise and Artifact Removal in Three-Dimensional Polarized Light Imaging

Conference paper (2021)

Authors

Kai Benning Forschungszentrum Jülich, Bergische Universität Wuppertal

Miriam Menzel Forschungszentrum Jülich

Jan André Reuter Forschungszentrum Jülich

Markus Axer Bergische Universität Wuppertal, Forschungszentrum Jülich

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Published Date

2021

Language

English

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Abstract

In recent years, Independent Component Analysis (ICA) has successfully been applied to remove noise and artifacts in images obtained from Three-dimensional Polarized Light Imaging (3D-PLI) at the mesoscale (i.e., 64 μ m). Here, we present an automatic denoising procedure for gray matter regions that allows to apply the ICA also to microscopic images, with reasonable computational effort. Apart from an automatic segmentation of gray matter regions, we applied the denoising procedure to several 3D-PLI images from a rat and a vervet monkey brain section.