Extracellular vesicle quantification and characterization

Common methods and emerging approaches

Review (2019)

Authors

Thomas A. Hartjes Erasmus MC
S. Mytnyk ChemE/Product and Process Engineering - AS
G. Jenster Erasmus MC
V. van Steijn ChemE/Product and Process Engineering - AS
M.E. van Royen Erasmus MC
Research Group
Education and Student Affairs
Copyright: © 2019 Thomas A. Hartjes, S. Mytnyk, G. Jenster, V. van Steijn, M.E. van Royen
DOI
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https://doi.org/10.3390/bioengineering6010007
Emerging technologies Extracellular vesicles (EVs) Methods for EV analysis
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Published Date

2019

Language

English

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Research Group

Education and Student Affairs

Abstract

Extracellular vesicles (EVs) are a family of small membrane vesicles that carry information about cells by which they are secreted. Growing interest in the role of EVs in intercellular communication, but also in using their diagnostic, prognostic and therapeutic potential in (bio) medical applications, demands for accurate assessment of their biochemical and physical properties. In this review, we provide an overview of available technologies for EV analysis by describing their working principles, assessing their utility in EV research and summarising their potential and limitations. To emphasise the innovations in EV analysis, we also highlight the unique possibilities of emerging technologies with high potential for further development.