Extracellular vesicle quantification and characterization

Common methods and emerging approaches

Review (2019)
Author(s)

Thomas A. Hartjes (Erasmus MC)

Serhii Mytnyk (TU Delft - ChemE/Product and Process Engineering)

G. Jenster (Erasmus MC)

Volkert Van Steijn (TU Delft - ChemE/Product and Process Engineering)

Martin E. van Royen (Erasmus MC)

Research Group
Education and Student Affairs
Copyright
© 2019 Thomas A. Hartjes, S. Mytnyk, G. Jenster, V. van Steijn, M.E. van Royen
DOI related publication
https://doi.org/10.3390/bioengineering6010007
More Info
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Publication Year
2019
Language
English
Copyright
© 2019 Thomas A. Hartjes, S. Mytnyk, G. Jenster, V. van Steijn, M.E. van Royen
Research Group
Education and Student Affairs
Issue number
1
Volume number
6
Reuse Rights

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Abstract

Extracellular vesicles (EVs) are a family of small membrane vesicles that carry information about cells by which they are secreted. Growing interest in the role of EVs in intercellular communication, but also in using their diagnostic, prognostic and therapeutic potential in (bio) medical applications, demands for accurate assessment of their biochemical and physical properties. In this review, we provide an overview of available technologies for EV analysis by describing their working principles, assessing their utility in EV research and summarising their potential and limitations. To emphasise the innovations in EV analysis, we also highlight the unique possibilities of emerging technologies with high potential for further development.

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