A solvent-free synthesis of (thio)ester derivatives using FeCl<sub>3</sub> as a heterogeneous catalyst

Journal article (2023)

Authors

S.H.H. Younes BT/Biocatalysis - AS , Sohag University
F. Hollmann BT/Biocatalysis - AS
Research Group
BT/Biocatalysis (AS) (TU Delft)
Copyright: © 2023 S.H.H. Younes, F. Hollmann
DOI
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https://doi.org/10.1016/j.tetlet.2023.154524
FeCl Thioester
More Info
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Published Date

2023

Language

English

Faculty

Applied Sciences

Department

BT/Biotechnologie

Research Group

BT/Biocatalysis

Abstract

A simple, solvent-free method for the synthesis of (thio)esters from simple acid chlorides at room temperature is reported. Simple FeCl3 (5 mol%) enables facile, near complete conversion of equimolar starting materials in high selectivity. Recycling of the catalyst has been demonstrated.