Infrared thermography

a scoping review of its possible role in the diagnosis and follow-up of leprosy neuropathy

Review (2025)
Author(s)

J. Wim Brandsma (Independent researcher)

Corine Knulst-Verlaan (INF Green Pastures Hospital & Rehabilitation Center)

A.J. Knulst (TU Delft - Medical Instruments & Bio-Inspired Technology, INF Green Pastures Hospital & Rehabilitation Center)

Suraj Maharjan (INF Green Pastures Hospital & Rehabilitation Center)

Research Group
Medical Instruments & Bio-Inspired Technology
DOI related publication
https://doi.org/10.47276/lr.96.3.2025040
More Info
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Publication Year
2025
Language
English
Research Group
Medical Instruments & Bio-Inspired Technology
Issue number
3
Volume number
96
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Abstract

Summary Neuropathy is a well-known complication of leprosy. Nerve palpation and assessment of motor and sensory nerves are routinely performed at diagnosis in leprosy, which helps establish the diagnosis and, during treatment, monitor the status of somatic nerve function. Assessment of peripheral autonomic nerve function is not commonly practiced for diagnosing leprosy or for diagnosing and monitoring neuropathy. Early impairments in autonomic function, however, may help to establish or confirm a diagnosis and predict the development of clinical leprosy and neuropathy. Several studies, including infrared thermography and electro-neurophysiological studies, have shown the presence of subclinical nerve impairments that may indicate a diagnosis of leprosy or lead to the development of neuropathy. Sudomotor and vasomotor impairments, in the presence of loss of protective sensation, also increase the risk for ulceration, often requiring chronic care. This article provides a brief discussion of the importance and assessment of peripheral autonomic nerve function in leprosy. Its focus is to review articles that have used infrared thermography to assess this function.