Developments in electrical-property tomography based on the contrast-source inversion method

Journal article (2019)

Authors

R.L. Leijsen Leiden University Medical Center
P.S. Fuchs Signal Processing Systems - EEMCS
Wyger Brink Leiden University Medical Center
A. Webb Leiden University Medical Center
R.F. Remis Signal Processing Systems - EEMCS
Research Group
Signal Processing Systems (EEMCS) (TU Delft)
Copyright: © 2019 R.L. Leijsen, P.S. Fuchs, Wyger Brink, A. Webb, R.F. Remis
DOI
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https://doi.org/10.3390/jimaging5020025
Magnetic resonance imaging Contrast-source inversion Electrical-property tomography Electromagnetic inverse scattering problems Nonlinear optimization
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Published Date

2019

Language

English

Faculty

Electrical Engineering, Mathematics and Computer Science

Department

Microelectronics

Research Group

Signal Processing Systems

Abstract


The main objective of electrical-property tomography (EPT) is to retrieve dielectric tissue parameters from B
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data as measured by a magnetic-resonance (MR) scanner. This is a so-called hybrid inverse problem in which data are defined inside the reconstruction domain of interest. In this paper, we discuss recent and new developments in EPT based on the contrast-source inversion (CSI) method. After a short review of the basics of this method, two- and three-dimensional implementations of CSI-EPT are presented along with a very efficient variant of 2D CSI-EPT called first-order induced current EPT (foIC-EPT). Practical implementation issues that arise when applying the method to measured data are addressed as well, and the limitations of a two-dimensional approach are extensively discussed. Tissue-parameter reconstructions of an anatomically correct male head model illustrate the performance of two- and three-dimensional CSI-EPT. We show that 2D implementation only produces reliable reconstructions under very special circumstances, while accurate reconstructions can be obtained with 3D CSI-EPT.