Peroxygenases en route to becoming dream catalysts. What are the opportunities and challenges?
Yonghua Wang (South China University of Technology)
Dongming Lan (South China University of Technology)
Rabia Durrani (South China University of Technology)
Frank Hollmann (TU Delft - Applied Sciences)
More Info
expand_more
Other than for strictly personal use, it is not permitted to download, forward or distribute the text or part of it, without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license such as Creative Commons.
Abstract
Peroxygenases are promising catalysts for preparative oxyfunctionalization chemistry as they combine the versatility of P450 monooxygenases with simplicity of cofactor-independent enzymes. Though many interesting applications have been reported, today ‘we have only scratched the surface’ and significant efforts are necessary to solve issues related to selectivity of the wild type enzymes and low product titers. For this, further elucidation of the vast natural diversity as well as protein and reaction engineering approaches are discussed.
help_outline