Unraveling proteins at the single molecule level using nanopores
Laura Restrepo Perez (TU Delft - Applied Sciences)
Cees Dekker – Promotor (TU Delft - Applied Sciences)
Chirlmin Joo – Promotor (TU Delft - Applied Sciences)
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Abstract
The function and phenotype of a cell is determined by a complex network of interactions between DNA, RNA, proteins and metabolites. Therefore, a comprehensive approach that integrates genomics, transcriptomics, proteomics, and metabolomics is necessary to achieve full understanding of biological processes and disease. Recent technological developments have mostly focused on the study of genomes. DNA sequencing has become fast, cheap, and ubiquitous. The study of other -omes, especially the proteome, remains expensive and time-consuming...