Thermo-elastic optical coherence tomography
Tianshi Wang (Erasmus MC)
Tom Pfeiffer (University of Lübeck)
Min Wu (Erasmus MC)
Wolfgang Wieser (Optores GmbH)
Gaetano Amenta (Erasmus MC)
Wolfgang Draxinger (University of Lübeck)
Antonius F.W. Van Der Steen (Chinese Academy of Sciences, Erasmus MC, ImPhys/Acoustical Wavefield Imaging )
Robert Huber (University of Lübeck)
Gijs Van Soest (Erasmus MC)
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Abstract
The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the optical absorption is a dominating factor for the displacement. Thermo-elastic OCT is capable of visualizing inclusions that do not appear on the structural OCT image, providing additional tissue type information.
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