Hybrid Control for Improved Pressure and Flow Tracking in Mechanical Ventilation

Journal Article (2026)
Author(s)

Lars van de Kamp (Demcon Life Sciences and Health)

Isabelle Franklin (Demcon Life Sciences and Health)

Bas van Loon (Demcon Life Sciences and Health)

Nathan van de Wouw (Eindhoven University of Technology)

Tom Oomen (Eindhoven University of Technology, TU Delft - Mechanical Engineering)

Research Group
Team Jan-Willem van Wingerden
DOI related publication
https://doi.org/10.1109/TCST.2026.3661100 Final published version
More Info
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Publication Year
2026
Language
English
Research Group
Team Jan-Willem van Wingerden
Journal title
IEEE Transactions on Control Systems Technology
Issue number
3
Volume number
34
Pages (from-to)
1204-1216
Downloads counter
1
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Abstract

Mechanical ventilators are essential for patients who are unable to breathe independently. The aim of this article is to develop a systematic control design methodology that achieves accurate tracking of both the pressure and flow to ensure comfortable breathing for the patient. A hybrid controller is introduced that ensures improved baseflow tracking performance. The actual controller design leverages frequency-based techniques and is based on static decoupling and the factorized Nyquist criterion. Furthermore, a theoretical stability analysis of the hybrid controller is presented. The presented control strategy is implemented in a real ventilator, and it is demonstrated that the tracking performance is improved by conducting an experimental case study.