Ultrasonically Powered and Controlled Microsystem for Dual-Wavelength Optogenetics with a Multi-Load Regulation Scheme

Journal Article (2023)
Author(s)

Amin Rashidi (TU Delft - Bio-Electronics)

Milad Zamani (TU Delft - Bio-Electronics, Aarhus University)

Tanmay Mondal (Tyndall National Institute)

Seyedsina Hosseini (Technical University of Denmark (DTU))

Kjeld Laursen (Aarhus University)

Brian Corbet (Tyndall National Institute)

Farshad Moradi (Aarhus University)

Research Group
Bio-Electronics
DOI related publication
https://doi.org/10.1109/LSSC.2023.3239601 Final published version
More Info
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Publication Year
2023
Language
English
Research Group
Bio-Electronics
Volume number
6
Pages (from-to)
33-36
Downloads counter
223
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Abstract

This letter presents an ultrasonically powered dual-wavelength optogenetic device that targets simultaneous excitation and inhibition of neural activities, or in a broader sense, optical stimulation in two distinct wavelengths for targeting different populations of neurons. This can be applied to a variety of neurological disorders. The device features a load regulator circuit that shares the available power budget between two LEDs in a power-efficient and controlled way suppressing the need for adaptive matching and overvoltage protection circuits. Furthermore, the regulator circuit is capable of detecting power burst availability on the device and generating a control signal, accordingly. For 5.25 -mW acoustic power at the device's surface, the rectified voltage, and the total current load of the system are regulated to 2.79 V and 600A , respectively. The maximum chip and device efficiencies of 92.5% and 31.8% are measured, respectively. The total die area in 180- nm CMOS technology nose and the estimated system volume are 0.16/2 and 0.572/3 , respectively.

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