Ultrasonically Powered and Controlled Microsystem for Dual-Wavelength Optogenetics with a Multi-Load Regulation Scheme
Amin Rashidi (TU Delft - Electrical Engineering, Mathematics and Computer Science)
Milad Zamani (TU Delft - Electrical Engineering, Mathematics and Computer Science, Aarhus University)
Tanmay Mondal (Tyndall National Institute)
Seyedsina Hosseini (Technical University of Denmark (DTU))
Kjeld Laursen (Aarhus University)
Brian Corbet (Tyndall National Institute)
Farshad Moradi (Aarhus University)
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Abstract
This letter presents an ultrasonically powered dual-wavelength optogenetic device that targets simultaneous excitation and inhibition of neural activities, or in a broader sense, optical stimulation in two distinct wavelengths for targeting different populations of neurons. This can be applied to a variety of neurological disorders. The device features a load regulator circuit that shares the available power budget between two LEDs in a power-efficient and controlled way suppressing the need for adaptive matching and overvoltage protection circuits. Furthermore, the regulator circuit is capable of detecting power burst availability on the device and generating a control signal, accordingly. For 5.25 -mW acoustic power at the device's surface, the rectified voltage, and the total current load of the system are regulated to 2.79 V and 600A , respectively. The maximum chip and device efficiencies of 92.5% and 31.8% are measured, respectively. The total die area in 180- nm CMOS technology nose and the estimated system volume are 0.16/2 and 0.572/3 , respectively.