Pigmented paraaxillary located “complex” basal cell carcinoma imitating clinically irritated melanocytic lesion -succesfull surgical approach in Bulgarian patient
Cristiana Voicu (Polisano Clinic)
Mara Madalina Mihai (Carol Davila University of Medicine and Pharmacy)
Mihai Lupu (Medas Medical Centre)
James W. Patterson (University of Virginia Health System)
Nely Koleva (Medical Institute of Ministry of Interior (MVR))
Uwe Wollina (Academic Teaching Hospital Dresden-Friedrichstadt)
Torello Lotti (TU Delft - BT/Environmental Biotechnology, Sapienza University of Rome)
Jacopo Lotti (Sapienza University of Rome)
Katlein França (University of Miami Miller School of Medicine)
Atanas Batashki (Medical University of Plovdiv)
Serena Gianfaldoni (University G. Marconi of Rome)
Ilko Bakardzhiev (Medical University of Varna)
Hristo Mangarov (Medical Institute of Ministry of Interior (MVR))
Georgi Tchernev (Onkoderma” - Policlinic for Dermatology, Medical Institute of Ministry of Interior (MVR))
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Abstract
Background: Basal cell carcinoma (BCC) is the most frequently encountered neoplasm worldwide. While nodular BCC is the most frequent clinical subtype, other forms of BCC, such as superficial, cystic, morpheiform, infiltrative, and pigmented may also be encountered. CASE PRESENTATION: We present the case of a 67-year-old male with a relatively well-defined infiltrative, pigmented plaque with multiple colours and peripheral growth situated in the right axillary region. The histopathologic examination performed after complete surgical excision of the tumour revealed a complex pigmented BCC with macronodular, fibroepithelioma-like, cystic, focally infiltrative and basosquamous features. Conclusion: Uncommon locations of BCCs in sun-protected areas such as the axillary region require a higher degree of suspicion for diagnosis. The complex histology of the presented case, including subtypes with differing biologic attributes, emphasises the importance of histopathological examination in the diagnosis and therapeutic management of BCC.
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