Biocatalysis explained

From pharmaceutical to bulk chemical production

Review (2019)
Authors

Eman Abdelraheem (TU Delft - BT/Biocatalysis, Sohag University)

Hanna Busch (TU Delft - BT/Biocatalysis)

Ulf Hanefeld (TU Delft - BT/Biocatalysis)

Fabio Tonin (TU Delft - BT/Biocatalysis)

Research Group
BT/Biocatalysis
Copyright
© 2019 E.M.M. Abdelraheem, H. Busch, U. Hanefeld, F. Tonin
To reference this document use:
https://doi.org/10.1039/c9re00301k
More Info
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Publication Year
2019
Language
English
Copyright
© 2019 E.M.M. Abdelraheem, H. Busch, U. Hanefeld, F. Tonin
Research Group
BT/Biocatalysis
Issue number
11
Volume number
4
Pages (from-to)
1878-1894
DOI:
https://doi.org/10.1039/c9re00301k
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Abstract

Biocatalysis is one of the most promising technologies for the sustainable synthesis of molecules for pharmaceutical, biotechnological and industrial purposes. From the gram to the ton scale, biocatalysis is employed with success. This is underpinned by the fact that the global enzyme market is predicted to increase from $7 billion to $10 billion by 2024. This review concentrates on showing the strong benefits that biocatalysis and the use of enzymes can provide to synthetic chemistry. Several examples of successful implementations of enzymes are discussed highlighting not only high-value pharmaceutical processes but also low-cost bulk products. Thus, biocatalytic methods make the chemistry more environmentally friendly and product specific.