The nocebo effect in psychotherapy

Review (2026)
Author(s)

Andrea W.M. Evers (Universiteit Leiden, TU Delft - Society, Culture and Critique, Erasmus Universiteit Rotterdam)

Research Group
Society, Culture and Critique
DOI related publication
https://doi.org/10.1016/j.copsyc.2025.102152
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Publication Year
2026
Language
English
Research Group
Society, Culture and Critique
Bibliographical Note
Green Open Access added to TU Delft Institutional Repository as part of the Taverne amendment. More information about this copyright law amendment can be found at https://www.openaccess.nl. Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.@en
Volume number
67
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Abstract

The nocebo effect, negative treatment outcomes arising from patient expectations, therapeutic context, or clinician communication, plays a possibly significant yet often underestimated role in psychotherapy. Drawing on recent empirical and theoretical contributions, possible mechanisms how nocebo effects occur and can be attenuated in psychotherapeutic practice are discussed. Nocebo effects may arise from therapist communication, previous treatment failures, adverse therapeutic dynamics, poorly managed expectations, social influences outside the therapy, or context factors elements such as waiting lists. Strategies for mitigating such effects include, for example, empathic engagement, expectation management, and reconditioning of previous negative treatment experiences in clinical settings.

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