A major step forward toward high-resolution nanopore sequencing of full-length proteins
M.H. Choi (TU Delft - BN/Chirlmin Joo Lab)
C. Joo (Ewha Womans University, TU Delft - BN/Chirlmin Joo Lab)
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Abstract
In a recent publication in Nature, Motone et al. report the development of a protein sequencing method using nanopores that enables the reading of long protein strands. This method allows for multi-pass re-reading and can detect single amino acid substitutions as well as post-translational modifications (PTMs).