Finite Element Simulation of Light and Correlation Propagation in Tissue

A finite element model simulation of diffuse optics in static and dynamic conditions

Master thesis (2023)

Authors

W. GUO Mechanical Engineering

Contributors

N. Bhattacharya ImPhys/Medical Imaging - AS (supervisor 1)
Sophinese Iskander-Rizk Optical Technologies - Mechanical, Maritime and Materials Engineering (coach)
B Zhang (coach)
Faculty
Mechanical Engineering
Copyright: © 2023 Wenpei GUO
More Info
expand_more

Published Date

24-08-2023

Language

English

Reuse Rights

Other than for strictly personal use, it is not permitted to download, forward or distribute the text or part of it, without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license such as Creative Commons.

Faculty

Mechanical Engineering

Abstract

The investigation of the interaction between lasers and brain tissue holds significant theoretical and practical significance in the field of brain physiology studies. A two-dimensional finite element-based simulation model was constructed using the commercial finite element simulation software COMSOL Multiphysics to investigate the propagation of light and photon correlation in tissues. The simulations included static and dynamic conditions of light propagation in tissue. In both cases this diffuse light propagation itself was studied along with photon correlation using the solution of the diffusion equation. Subsequently, the obtained simulation results are assessed and summarized by considering the outcomes of data fitting. The findings indicate that the accuracy of simulating light propagation is higher for larger sizes, although satisfactory results can be achieved for correlation propagation simulations in the small size range. The simulation results remain unaffected by the refinement of the mesh, provided that the fundamental criteria for mesh size are satisfied.