Calculating the motion of highly confined, arbitrary-shaped particles in Hele–Shaw channels

Journal Article (2018)
Author(s)

Bram Bet (Universiteit Utrecht)

Rumen Georgiev (TU Delft - Mechanical Engineering, Universiteit Utrecht)

William Uspal (University of Stuttgart, Max Planck Institute for Intelligent Systems)

Huseyin Burak Eral (TU Delft - Mechanical Engineering, Universiteit Utrecht)

René van Roij (Universiteit Utrecht)

Sela Samin (Universiteit Utrecht)

Research Group
Intensified Reaction and Separation Systems
DOI related publication
https://doi.org/10.1007/s10404-018-2092-y Final published version
More Info
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Publication Year
2018
Language
English
Research Group
Intensified Reaction and Separation Systems
Journal title
Microfluidics and Nanofluidics
Issue number
8
Volume number
22
Article number
77
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231
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Abstract

We combine theory and numerical calculations to accurately predict the motion of anisotropic particles in shallow microfluidic channels, in which the particles are strongly confined in the vertical direction. We formulate an effective quasi-two-dimensional description of the Stokes flow around the particle via the Brinkman equation, which can be solved in a time that is two orders of magnitude faster than the three-dimensional problem. The computational speedup enables us to calculate the full trajectories of particles in the channel. To validate our scheme, we study the motion of dumbbell-shaped particles that are produced in a microfluidic channel using ‘continuous-flow lithography’. Contrary to what was reported in earlier work (Uspal et al. in Nat Commun 4:2666, 2013), we find that the reorientation time of a dumbbell particle in an external flow exhibits a minimum as a function of its disk size ratio. This finding is in excellent agreement with new experiments, thus confirming the predictive power of our scheme.